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What is Ambien: Uses, Warnings & Interactions
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Updated May 28, 2024  •  Published Dec 30, 2020
Ambien is a brand-name prescription drug used to help people fall asleep. People with problems falling and staying asleep can take the extended-release version Ambien CR. Ambien’s active ingredient, zolpidem tartrate, is a sedative-hypnotic, a type of drug that slows down the brain and induces sleep. People having trouble falling asleep will take a dose right before bedtime. Because of possible risks, Ambien is only intended for the short-term treatment of insomnia.

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Ambien overview
BRAND NAMES:
Ambien, Ambien CR

Generic Names:
Zolpidem tartrate

Uses:
Treats insomnia

Therapeutic Classes:
Sedative-hypnotic, non-benzodiazepine GABA receptor agonist

Forms:
Tablet, extended-release tablet

How it’s taken:
By mouth

What is Ambien used for?
Ambien is a short-term treatment for insomnia characterized by problems with sleep initiation, that is, problems falling asleep after going to bed. Extended-release Ambien CR is a short-term treatment for insomnia in people who have problems falling asleep, staying asleep, or both.

What form(s) does Ambien come in
Tablet

5 mg

10 mg

Extended-release tablet

6.25 mg

12.5 mg

What are common Ambien doses?
For insomnia: 5 or 10 mg Ambien tablet OR 6.25 or 12.5 Ambien CR tablet taken immediately before bedtime

RELATED: Ambien dosage, forms, and strengths

Common Ambien prescriptions
Ambien 10 tablets bottle
Ambien
10 tablets bottle

Ambien 100 tablets bottle
Ambien
100 tablets bottle

Ambien 12 tablets bottle
Ambien
12 tablets bottle

Ambien 15 tablets bottle
Ambien
15 tablets bottle

Ambien 20 tablets bottle
Ambien
20 tablets bottle

Ambien 30 tablets bottle
Ambien
30 tablets bottle

Ambien 45 tablets bottle
Ambien
45 tablets bottle

Ambien 6 tablets bottle
Ambien
6 tablets bottle

Ambien 60 tablets bottle
Ambien
60 tablets bottle

Ambien 90 tablets bottle
Ambien
90 tablets bottle

Ambien 10mg tablet
Ambien
10mg tablet

Ambien 5mg tablet
Ambien
5mg tablet

How to take Ambien
Take Ambien exactly as prescribed. Do not change the dose.

Follow the doctor’s instructions. Ambien is only intended for short-term use.

Before taking Ambien, read the Medication Guide that comes with the medicine.

Do not take Ambien if you drank alcohol in the hours before going to sleep or right before going to sleep.

How to take an Ambien or Ambien CR tablet:

Take the Ambien dose right before bedtime if you have at least seven or eight hours of sleep or rest before you need to be active again.

Ambien works best on an empty stomach.

Swallow the tablet whole. Do not crush, break, or chew it.

Store Ambien or Ambien CR tablets at room temperature that are out of the reach of children.

What to do if you miss a dose of Ambien
Do not take a missed dose of Ambien if you do not have at least seven or eight hours to rest before you need to be active again.

Ambien contraindications
This medicine is not right for everyone.

Do not use it if you have had an allergic reaction to zolpidem or had any complex sleep behaviors like sleep-walking or sleep-driving when taking zolpidem.

Ambien warnings
Tell any doctor or other healthcare provider who treats you that you are using this medicine.

Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Call your doctor if you still have trouble sleeping after you take this medicine for 7 to 10 days.

Before taking Ambien, tell your doctor if you have:

Kidney disease

Liver disease

Lung disease (including COPD)

Breathing problems (including sleep apnea)

Myasthenia gravis

A history of depression or other mental health problems

Thoughts about suicide

A history of drug or alcohol abuse

Tell the doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Using this medicine during the last 3 months of your pregnancy (third trimester) can harm your newborn baby.

Do not breastfeed for 23 hours after taking a dose of Ambien, but pump and throw away breast milk instead.

This medicine may cause dizziness, drowsiness, decreased alertness, brain fog, clumsiness, or coordination problems, especially the next morning. You may be at an increased risk of accidents, falls, or injury. Do not drive or do anything else that requires alertness and coordination until these effects wear off.

This medicine may cause bizarre sleep behaviors such as sleep-walking, sleep-driving, cooking in your sleep, and similar behaviors. These behaviors are potentially hazardous and could lead to fatal injuries. Tell your doctor right away if you have learned that this has happened. Ambien will have to be discontinued.

Ambien can cause unusual moods, behaviors, or suicidal thoughts. Tell the doctor if you have problems with mood, depression, or thoughts of hurting yourself.

Ambien can be habit-forming and cause physical dependency. Do not use more than your prescribed dose or take Ambien for long periods. The inappropriate use of Ambien can lead to addiction or overdose.

An Ambien overdose can be fatal. Get immediate emergency medical care if too much Ambien is taken.

Do not stop using this medicine suddenly. Your doctor may need to decrease your dose slowly before you stop completely.

Ambien is a federally controlled substance. Giving or selling this drug to anyone else is dangerous and against the law.

Keep this medicine securely out of the reach of children.

Ambien interactions
Tell other healthcare providers you are using this medicine before they prescribe new medications.

To avoid potentially hazardous drug interactions, tell the prescribing healthcare provider about all prescription drugs, over-the-counter medications, and supplements you use before taking Ambien, especially:

Opioids

Benzodiazepines

Tricyclic antidepressants

Other medicines that make you sleepy

Do not take a dose of Ambien if you have had a drink of alcohol during the evening or at bedtime.

Ambien side effects
Serious side effects

Talk to a healthcare provider if you notice any signs or symptoms of a possible serious side effect, including:

Severe confusion, drowsiness, muscle weakness

Anxiety, agitation, depression, nervousness, unusual moods or behaviors, thoughts of hurting yourself

Seeing, hearing, or feeling things that are not there

Memory loss

Trouble breathing, blue lips, fingernails, or skin

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less serious side effects

Daytime drowsiness

Headache

Dizziness

Diarrhea

Grogginess (drugged feeling)

Find more detailed information about Ambien's side effects here.

Sources:
Ambien, Sanofi-Aventis

Ambien zolpidem tartrate tablet prescribing information, DailyMed (NIH National Library of Medicine)

Ambien CR zolpidem tartrate tablet prescribing information, DailyMed (NIH National Library of Medicine)

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Zolpidem Tartrate
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